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1. |
CHANGES IN ANTHROPOMETRIC, BODY COMPOSITION, CLINICAL PARAMETERS, BIOCHEMICAL PROFILES, AND BIOMARKERS CONCENTRATION OF SUBCLINICAL ATHEROSCLEROSIS OF THE EBN INTERVENTION AMONG PREMENOPAUSAL WOMEN: A RANDOMIZED CONTROL TRIAL
DESCRIPTION : Introduction: The menopausal transition is an important physiological stage in the lives of women that is associated with the risk of cardiovascular disease later in life. Objective: This study aimed to describe changes in anthropometric measurements, body composition, clinical parameters, biochemical profiles, biomarker concentration, and carotid ultrasound to address risk factors for subclinical atherosclerosis disease among premenopausal women with borderline hypercholesterolemia before and after intervention. This was a 12-week randomized control trial comparing an intervention with an edible bird nest with a control. Subjects: The study involved 39 premenopausal women 40-55 years of age who, following inclusion and exclusion criteria, were allocated into two groups, an intervention group consuming one (1) pouch (250 g) of edible bird nest mix (EBN) daily for 12 weeks (between days 84 and 90 days from day 1 of menses) and the control group consuming the same weight, texture and taste of the placebo. Main outcome measures: Assessment before and after inclusion of the anthropometric status parameters [weight, height, body mass index, hip, waist to hip ratio (WHR), body composition (body fat, body age, whole body skeletal, trunk skeletal, arm skeletal, leg skeletal, total body subcutaneous, trunk subcutaneous, arm subcutaneous, leg subcutaneous, visceral fat), clinical parameters (blood pressure (systolic and diastolic), thickness of the carotid intima, biochemical profiles (lipid profile, lasting blood glucose), biomarker concentrations (APO AI, APO AII, APO B, APO CII, APO CIII, APO E). This study showed that the EBN intervention for premenopausal women with mild hypercholesterolemia resulted in slightly beneficial changes in anthropometric measurement, body composition, clinical parameters, and biomarker concentration associated with cardiovascular risk in older women. These findings present a potential for the use of EBN in individuals with borderline hypercholesterolemia to provide cholesterol lowering benefit based on an animal-based diet strategy that can improve overall health outcomes when reaching menopausal age. CONTRIBUTOR : SALWANA BINTI AHMAD (25/12/2023 16:43 PM)
FACULTY : INSTITUT BIOSAINS
PUBLICATION : 0 ; FILE IN : HDFS HAS VIEWS : 1325 ; FOLDER IN PROJECT : 1 ; FILE IN PROJECT : 1 ; DOWNLOAD : 1 ; KEYWORD : [Biochemical profile] , [ subclinical atherosclerosis] , [ carotid intima media thickness] , [ ovary size] , [ vascular aging] , [ premenopausal women.] |
2. |
MASSIVE MSV000090428-SHEDDING LIGHT ON PIPER’S IDENTITY VIA COMPUTATIONAL MASS SPECTROMETRY
DESCRIPTION : Computational mass spectrometry study involving LC-MS/MS analysis of methanol extracts of lyophilized leaves of Piper rubro-venosum to assess whether the names Piper rubro-venosum and Piper crocatum refer to one species of Piper. CONTRIBUTOR : KHOZIRAH BINTI SHAARI (11/05/2023 10:55 AM)
FACULTY : INSTITUT BIOSAINS
PUBLICATION : 0 ; FILE IN : HDFS HAS VIEWS : 4281 ; FOLDER IN PROJECT : 1 ; FILE IN PROJECT : 0 ; DOWNLOAD : 0 ; KEYWORD : [Piper cf. fragile] , [ Piper] , [ Piper ornatum] , [ Piper fragile] , [ Piper crocatum] , [ Malaysia] , [ Neolignans] |
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