We found 1 data for "ardisia crispa"

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1.
POTENTIAL ANGIOPREVENTIVE AGENT OF BENZOQUINONOID COMPUND FROM ARDISIA CRISPA ROOT IN VITRO AND IN VIVO
DESCRIPTION : Ardisia crispa (Thunb) A.DC is a local medicinal plant traditionally claimed for its therapeutic use in various inflammatory-related diseases. Its root part has been scientifically validated to be effective in various inflammatory animal models. In this study, we isolated its bioactive compound (AC2) from the hexane fractionated extract of the plant's root (ACRH) and tested its antiangiogenic properties against human umbilical vein endothelial cells (HUVECs) and zebra fish assay, respectively. Our findings exhibited promising antiangiogenic effects of both AC2 and ACRH by suppressing its angiogenic signaling cascades, in vitro as well as significantly inhibited zebrafish embryo intersegmental vessels (ISVs), confirming its antiangiogenic role
CONTRIBUTOR : ROSLIDA BINTI ABD HAMID @ ABDUL RAZAK (29/12/2023 12:18 PM)
FACULTY : FAKULTI PERUBATAN DAN SAINS KESIHATAN
PUBLICATION : 1 ; FILE IN :
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KEYWORD : [Ardisia crispa] , [ 2-methoxy-6-undecyl-1] , [4-benzoquinone. HUVECs] , [ cell migration] , [ cell invasion] , [ tube formation] , [ VEGF]