We found 2 data for "microscopy"

LIST DATASET

NO. DATASET TITLE
1.
FORMULATION AND OPTIMIZATION OF NANOEMULSION DRUG DELIVERY SYSTEM CONTAINING PHENYTOIN FOR EPILEPSY TREATMENT
DESCRIPTION : Epilepsy is a central nervous system (CNS) disease whereby abnormal electrical activity is present in the brain resulting in seizures. Epileptic patients are prescribed with anti-epileptic or anti-convulsant drugs. Various approaches have been explored to treat the disease. However, challenges of modern anti-epileptic drugs (AEDs) nowadays are the difficulty of the drugs to penetrate the blood brain barrier (BBB) which results in poor efficacy thus many patients develops resistance against AEDs. Nanoemulsions have been increasingly developed for use as drug delivery systems. It offers several significant advantages including powerful permeation ability with high drug-loading capacity, enhanced bioavailability and drug stability. In this project, formulation of nanoemulsion containing phenytoin (PHT), an anticonvulsant drug will be prepared using a mixture of both low and high energy emulsification techniques. The optimization of nanoemulsion will be carried out using response surface methodology (RSM) and mixture design (MD) techniques. The investigations of the physicochemical properties of nanoemulsion such as particle size, morphology and the stability of the droplet size will be evaluated. The efficacy of the PHT from nanoemulsion will be tested in-vivo and in-vitro through blood brain barrier (BBB). By doing these tests PHT-loaded nano-emulsions could be promising carriers having the potential to improve the drug bioavailability in brain tissue.
CONTRIBUTOR : NORAZLINALIZA BINTI SALIM (11/05/2023 16:42 PM)
FACULTY : FAKULTI SAINS
PUBLICATION : 2 ; FILE IN :
HAS VIEWS : 70 ; FOLDER IN PROJECT : 0 ; FILE IN PROJECT : 0 ; DOWNLOAD : 0 ;
KEYWORD : [Epilepsy Treatment] , [ Nanoemulsion] , [ PHT-loaded nano-emulsions]
2.
MICROGRAPHS OF PINK PILL
DESCRIPTION : The pink pill sample stored in a sealed plastic straw was used without any modifications.
CONTRIBUTOR : MOHD RASHIDI BIN ABDULL MANAP (11/05/2023 10:54 AM)
FACULTY : FAKULTI SAINS
PUBLICATION : 0 ; FILE IN : HDFS 
HAS VIEWS : 1146 ; FOLDER IN PROJECT : 1 ; FILE IN PROJECT : 2 ; DOWNLOAD : 9 ;
KEYWORD : [Microscopy]