DATASETS MEDICINE

THE MALAYSIAN GESTATIONAL DIABETES AND PREVENTION OF DIABTES STUDY (MY GODDESS)

Over 50% of women with a history of gestational diabetes mellitus (GDM) will develop type 2 diabetes (T2D) in later life. Asian women experience a disproportionate risk of both GDM and T2D compared to women from other ethnic backgrounds. Lifestyle interventions and behavior change can delay or even prevent the onset of T2D. We have developed a digitalized diabetes prevention intervention for the prevention of T2D in Malaysian women with GDM.

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PUBLICATION

JOURNAL
Title : A protocol of process evaluations of interventions for the prevention of type 2 diabetes in women with gestational diabetes mellitus: a systematic Review
Description :
Background: Process evaluations of randomised controlled trials (RCTs) can provide insight and inform us on the intervention implementation, the causal mechanisms and the contextual factors. This will inform about interventions’ success or failure due to their implementation or the interventions themselves. We aim to consolidate the methodology from previous process evaluations of complex interventions upon their findings on facilitators and barriers to address the prevention of type 2 diabetes mellitus among women with gestational diabetes mellitus (GDM). Methods: Comprehensive search will be conducted on electronic databases and reference lists of recent reviews for RCTs of complex interventions which address process evaluations of diabetes prevention intervention (DPI) for women with GDM in healthcare settings. There is no restriction on the language of the papers and year of publication until December 2020. Data from each study will be extracted by two reviewers independently using standardised forms. Data extracted include descriptive items on the study design and the outcomes of process evaluations from the three dimensions: (1) implementation; (2) mechanism of impact and (3) context. The quality of the studies will be assessed using mixed methods appraisal tool which is designed for the appraisal of mixed studies in systematic reviews. A narrative and framework analysis of the findings will be presented to inform the contents of a new DPI for women with GDM. Discussion: The findings from this process evaluation findings are valuable in determining whether a complex intervention should be scaled up or modified for other contexts in future plan. It will give deeper understanding of potential challenges and solutions to aid in the implementation of effective DPIs for GDM in Malaysia.
Authors : MAZATULFAZURA SF BINTI SALIM,NURUL IFTIDA BINTI BASRI,BARAKATUN NISAK BINTI MOHD YUSOF,CHING SIEW MOOI,FAEZAH BINTI HASSAN,IRMI ZARINA BINTI ISMAIL
Date Publish : 03/09/2021
Title : Study protocol on risk factors for the diagnosis of gestational diabetes mellitus in different trimesters and their relation to maternal and neonatal outcomes (GDM-RIDMAN)
Description :
Introduction Gestational diabetes mellitus (GDM) is often associated with adverse pregnancy outcomes. However, the association of risk factors with GDM diagnosis, maternal and neonatal health outcomes is less established when compared with women without GDM. We aim to examine the diagnostic accuracy of the conventional and novel risk factors for a GDM diagnosis and their impact on maternal and neonatal health outcomes. Methods and analysis This retrospective cohort and nested case–control study at six public health clinics is based on medical records and questionnaire survey of women between 2 and 12 months postpartum. The estimated required sample size is 876 complete records (292 cases, 584 control, at a ratio of 1:2). Oral glucose tolerance test results will be used to identify glucose dysregulation, and maternal and neonatal outcomes include maternal weight gain, pre-eclampsia, polyhydramnios, mode of delivery, preterm or postdate birth, complications in labour, birth weight, gestational age at birth, Apgar score, congenital anomaly, congenital hypothyroidism, neonatal death or stillbirth, hypoglycaemia and hyperbilirubinaemia. Psychosocial measures include the WHO Quality of Life: brief, mother–infant bonding (14-item Postpartum Bonding Questionnaire and 19-item Maternal Postnatal Attachment Scale), anxiety (7-item Generalised Anxiety Disorder), depression (9-item Patient Health Questionnaire) and stress (Perceived Stress Scale symptoms) questionnaires. The comparative incidences of maternal and neonatal health outcomes, the comparative prevalence of the psychosocial outcomes between women with GDM and without GDM, specificity, sensitivity, positive and negative predictive values of the risk factors, separately and combined, will be reported. All GDM risk factors and outcomes will be modelled using multivariable regression analysis and the receiver operating characteristics curve will be reported.
Authors : INTAN NURESLYNA BINTI SAMSUDIN,NURUL IFTIDA BINTI BASRI
URL :
1) https://bmjopen.bmj.com/content/12/7/e052554

Date Publish : 29/09/2022
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Organization (Faculty)

Fakulti Perubatan Dan Sains Kesihatan [25]
Fakulti Sains [18]
Fakulti Bioteknologi Dan Sains Biomolekul [6]
Fakulti Sains Komputer Dan Teknologi Maklumat [1]
Fakulti Bahasa Moden Dan Komunikasi [2]
Fakulti Kejuruteraan [2]
Institut Pertanian Tropika Dan Sekuriti Makanan [1]
Institut Gerontologi [2]
Institut Biosains [2]
Fakulti Sains Dan Teknologi Makanan [1]
Pusat Pembangunan Maklumat Dan Komunikasi [1]
Fakulti Ekonomi Dan Pengurusan [2]
Fakulti Perubatan Veterinar [4]
Fakulti Pertanian [8]
Fakulti Ekologi Manusia [2]
Institut Penyelidikan Produk Halal [1]
Institut Penyelidikan Matematik [1]
Fakulti Sains Pertanian Dan Makanan [2]
Institut Perhutanan Tropika Dan Produk Hutan [2]
Kampus Upm Bintulu [1]
Fakulti Perhutanan [6]

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Agricultural And Biological Sciences [13]
Biochemistry, Genetics And Molecular Biology [12]
Chemical Engineering [1]
Chemistry [11]
Computer Science [3]
Earth And Planetary Sciences [1]
Economics, Econometrics And Finance [1]
Energy [4]
Engineering [3]
Environmental Science [16]
Health Professions [1]
Immunology And Microbiology [4]
Materials Science [14]
Mathematics [1]
Medicine [29]
Pharmacology, Toxicology And Pharmaceutics [2]
Psychology [1]
Social Sciences [7]
Veterinary [5]

Keyword

[gestational diabetes mellitus] , [ diabetes prevention] , [ randomized controlled trial] , [ mobile app]